RGS18

Across TCGA cell cohorts, RGS18 protein abundance is significantly associated with the RNA expression of many other genes, with 2,273 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible RGS18-associated genes across cancer lineages are PROCR, RAB25, and ILDR1. Each is linked with RGS18 in more than 14 cancer types. Because this analysis shows association rather than direction, both RGS18-to-partner and partner-to-RGS18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS18 versus PROCR in LUNG_SCLC, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS18→partner) and Y-score (partner→RGS18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	PROCR →	+3.237	+3.002	<.001	.001	3	15
URINARY_TRACT	RAB25 →	-5.052	-1.892	.009	.009	3	6
LARGE_INTESTINE	ILDR1 →	-1.612	-2.141	<.001	.001	3	6
SKIN	ASPHD1 →	+1.516	+1.388	.002	.001	3	6
LARGE_INTESTINE	STX2 →	+1.165	+1.789	.001	.001	3	5
LUNG_NSCLC_LUAD	APC2 →	+0.790	+2.665	.004	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,273 associations by consensus.

RGS18 vs PROCR — LUNG_SCLC

Explore this scatter interactively →