RGS17

Across TCGA cell cohorts, RGS17 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RGS17-associated genes across cancer lineages are OR2C1 and H1-6. Each is linked with RGS17 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGS17-to-partner and partner-to-RGS17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2C1 grouped by RGS17-low versus RGS17-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS17→partner) and Y-score (partner→RGS17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR2C1 →	+0.101	+3.578	.002	.006	3	1
LARGE_INTESTINE	H1-6 →	+0.113	+3.509	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR2C1 by RGS17 expression — LARGE_INTESTINE

Explore this box plot interactively →