RGS12

Across TCGA patient cohorts, RGS12 protein abundance is significantly associated with the RNA expression of many other genes, with 15,395 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RGS12-associated genes across cancer lineages are BMERB1, NOP14-AS1, and MAST4. Each is linked with RGS12 in more than 4 cancer types. Because this analysis shows association rather than direction, both RGS12-to-partner and partner-to-RGS12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS12 versus BMERB1 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS12→partner) and Y-score (partner→RGS12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BMERB1 →	+0.972	+0.277	<.001	<.001	3	5
LSCC	NOP14-AS1 →	+0.615	+0.372	<.001	<.001	3	5
BRCA	MAST4 →	+1.223	+0.351	<.001	<.001	3	4
BRCA	ARHGAP32 →	+0.890	+0.297	.002	.006	3	4
LSCC	DHX15 →	+0.455	+0.376	<.001	<.001	3	4
BRCA	FBXL5 →	+0.686	+0.340	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,395 associations by consensus.

RGS12 vs BMERB1 — BRCA

Explore this scatter interactively →