RGPD8

Across TCGA cell cohorts, RGPD8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,863 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RGPD8-associated GO terms across cancer lineages are Heterochromatin formation, Negative regulation of gene expression, epigenetic, and mRNA export from nucleus. Each is linked with RGPD8 in more than 15 cancer types. Because this analysis shows association rather than direction, both RGPD8-to-partner and partner-to-RGPD8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin formation grouped by RGPD8-low versus RGPD8-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGPD8→partner) and Y-score (partner→RGPD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Heterochromatin formation →	+0.073	+0.625	<.001	<.001	3	16
BONE	Negative regulation of gene expression, epigenetic →	+0.076	+0.590	<.001	<.001	3	16
STOMACH	mRNA export from nucleus →	+0.089	+0.972	.007	.005	3	15
UPPER_AERODIGESTIVE_TRACT	Nucleocytoplasmic transport →	+0.078	+1.046	<.001	<.001	3	15
STOMACH	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.093	+1.182	.008	.003	3	15
BONE	Epigenetic regulation of gene expression →	+0.059	+0.598	.003	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,863 associations by consensus.

Heterochromatin formation by RGPD8 expression — BONE

Explore this box plot interactively →