RGPD8

Across TCGA cell cohorts, RGPD8 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RGPD8-associated genes across cancer lineages are OR4F4, ELOA3DP, and OR6Q1. Each is linked with RGPD8 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGPD8-to-partner and partner-to-RGPD8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4F4 grouped by RGPD8-low versus RGPD8-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGPD8→partner) and Y-score (partner→RGPD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR4F4 →	+0.017	+4.273	.001	.006	3	1
LARGE_INTESTINE	ELOA3DP →	+0.026	+4.273	<.001	.006	3	1
LARGE_INTESTINE	OR6Q1 →	+0.022	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR4F4 by RGPD8 expression — LARGE_INTESTINE

Explore this box plot interactively →