RGPD6

Across TCGA cell cohorts, RGPD6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,742 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RGPD6-associated GO terms across cancer lineages are Protein localization to lysosome, Termination of RNA polymerase II transcription, and Heterochromatin organization. Each is linked with RGPD6 in more than 13 cancer types. Because this analysis shows association rather than direction, both RGPD6-to-partner and partner-to-RGPD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to lysosome grouped by RGPD6-low versus RGPD6-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGPD6→partner) and Y-score (partner→RGPD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Protein localization to lysosome →	+0.103	+1.003	.002	<.001	3	14
SOFT_TISSUE	Termination of RNA polymerase II transcription →	+0.107	+0.831	<.001	.002	3	14
BONE	Heterochromatin organization →	+0.084	+0.805	<.001	<.001	3	14
BONE	Negative regulation of myoblast fusion →	+0.118	+0.971	<.001	<.001	3	13
OESOPHAGUS	Positive regulation of cytoplasmic translation →	+0.116	+1.036	<.001	<.001	3	13
BONE	Heterochromatin formation →	+0.086	+0.805	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,742 associations by consensus.

Protein localization to lysosome by RGPD6 expression — LUNG_SCLC

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