RGPD5

Across TCGA patient cohorts, RGPD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,753 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RGPD5-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, Protein modification by small protein removal, and Vesicle-mediated transport to the plasma membrane. Each is linked with RGPD5 in more than 25 cancer types. Because this analysis shows association rather than direction, both RGPD5-to-partner and partner-to-RGPD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay grouped by RGPD5-low versus RGPD5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGPD5→partner) and Y-score (partner→RGPD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.062	+0.024	<.001	<.001	3	26
STAD	Protein modification by small protein removal →	+0.057	+0.026	<.001	<.001	3	25
STAD	Vesicle-mediated transport to the plasma membrane →	+0.055	+0.023	<.001	<.001	3	24
STAD	Protein targeting to lysosome →	+0.060	+0.023	<.001	<.001	3	24
STAD	Protein targeting to vacuole →	+0.058	+0.021	<.001	<.001	3	24
STAD	Negative regulation of telomere maintenance →	+0.056	+0.026	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,753 associations by consensus.

Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay by RGPD5 expression — STAD

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