RGPD5

Across TCGA cell cohorts, RGPD5 protein abundance is significantly associated with the go_rna of many other GO terms, with 316 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RGPD5-associated GO terms across cancer lineages are Maintenance of organelle location, Negative regulation of striated muscle cell apoptotic process, and Polyol transmembrane transport. Each is linked with RGPD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGPD5-to-partner and partner-to-RGPD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of organelle location grouped by RGPD5-low versus RGPD5-high in LARGE_INTESTINE.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGPD5→partner) and Y-score (partner→RGPD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Maintenance of organelle location →	+0.046	+1.133	.003	.001	3	2
LUNG_NSCLC_LUAD	Negative regulation of striated muscle cell apoptotic process →	+0.134	+2.065	.005	<.001	3	2
LUNG_NSCLC_LUAD	Polyol transmembrane transport →	+1.342	+2.028	.003	<.001	3	2
LUNG_NSCLC_LUAD	Regulation of excitatory synapse assembly →	+0.159	+2.347	<.001	.001	3	2
LUNG_NSCLC_LUAD	B cell proliferation →	+0.279	+1.962	<.001	<.001	3	2
OESOPHAGUS	Positive regulation of endoplasmic reticulum tubular network organization →	-0.154	-1.330	.007	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 316 associations by consensus.

Maintenance of organelle location by RGPD5 expression — LARGE_INTESTINE

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