Across TCGA patient cohorts, RGPD4 mutation is significantly associated with the RNA expression of many other genes, with 4,648 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RGPD4-associated genes across cancer lineages are NDUFAF5, DAZAP1, and GUF1. Each is linked with RGPD4 in more than 4 cancer types. Because this analysis shows association rather than direction, both RGPD4-to-partner and partner-to-RGPD4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGPD4→partner) and Y-score (partner→RGPD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NDUFAF5 →	+0.276	+1.473	<.001	.002	3	5
SKCM	DAZAP1 →	+0.241	+1.683	<.001	<.001	3	5
UCEC	GUF1 →	+0.392	+2.364	<.001	<.001	3	4
UCEC	SLBP →	+0.368	+1.770	.005	<.001	3	4
UCEC	FBXO22 →	+0.384	+1.617	<.001	<.001	3	4
UCEC	UQCRH →	+0.615	+1.797	.005	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,648 associations by consensus.

Exploration

RGPD4 survival (RNA) · tumor vs normal (RNA) · all RGPD4 data types