RGP1

Across TCGA pan-cancer cohorts, RGP1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RGP1 data layer compared with 28 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher RGP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RGP1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

PDAC, HNSC, and LSCC are the cancer types where RGP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.196	0.389	.003	32	view →
HNSC	OS	Median	All	1.000	0.479	.049	12	view →
LSCC	DFS	Quartile	II,III,IV	0.710	0.963	.013	8	view →
LUAD	DFS	Median	II,III,IV	0.903	0.787	.026	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RGP1–PDAC (DFS)

Open the PDAC breakdown →