RGMB-AS1

Across TCGA pan-cancer cohorts, RGMB-AS1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RGMB-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where RGMB-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types RGMB-AS1 is over-expressed in tumor, although a few such as STAD and KIRC show the opposite, repressed pattern.

STAD, KIRC, and PRAD are the cancer types where RGMB-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RGMB-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	All	−0.480	.004	6	view →
KIRC	Male	All	−0.223	<.001	5	view →
PRAD	All	All	+0.818	<.001	2	view →
LUAD	Male	III,IV	−0.413	.004	2	view →
LUSC	All	III,IV	−0.380	.009	2	view →
ESCA	All	All	−1.170	.021	1	view →
BLCA	Female	III,IV	+0.488	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RGMB-AS1–STAD

Open the STAD breakdown →