RGMA

Across TCGA patient cohorts, RGMA RNA expression is significantly associated with the protein abundance of many other proteins, with 18,788 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RGMA-associated proteins across cancer lineages are SORBS1, TMOD1, and DDAH2. Each is linked with RGMA in more than 5 cancer types. Because this analysis shows association rather than direction, both RGMA-to-partner and partner-to-RGMA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGMA versus SORBS1 in COAD, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RGMA→partner) and Y-score (partner→RGMA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SORBS1 →	+0.799	+0.520	<.001	<.001	3	6
BRCA	TMOD1 →	+0.731	+0.648	<.001	<.001	3	6
COAD	DDAH2 →	+0.361	+0.419	<.001	<.001	3	6
COAD	FERMT2 →	+0.747	+0.725	<.001	<.001	3	6
LSCC	ITPKB →	+0.486	+1.074	<.001	<.001	3	6
BRCA	MCAM →	+0.631	+0.913	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,788 associations by consensus.

RGMA vs SORBS1 — COAD

Explore this scatter interactively →