RGMA

Across TCGA patient cohorts, RGMA protein abundance is significantly associated with the RNA expression of many other genes, with 3,916 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RGMA-associated genes across cancer lineages are BMP7, SLC17A9, and TNPO2. Each is linked with RGMA in more than 1 cancer types. Because this analysis shows association rather than direction, both RGMA-to-partner and partner-to-RGMA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGMA versus BMP7 in LSCC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGMA→partner) and Y-score (partner→RGMA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BMP7 →	+1.796	+0.649	<.001	.003	3	2
LSCC	SLC17A9 →	-0.917	-0.989	<.001	<.001	3	2
LSCC	TNPO2 →	+0.735	+0.853	.001	<.001	3	2
LSCC	PTCD1 →	+0.595	+1.095	<.001	<.001	3	2
LSCC	PTPRZ1 →	+3.283	+1.267	<.001	<.001	3	2
LSCC	ITK →	-0.831	-0.640	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,916 associations by consensus.

RGMA vs BMP7 — LSCC

Explore this scatter interactively →