RFXAP

Across TCGA patient cohorts, RFXAP RNA expression is significantly associated with the protein abundance of many other proteins, with 12,166 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RFXAP-associated proteins across cancer lineages are HMGB1, GPALPP1, and ZMYM2. Each is linked with RFXAP in more than 5 cancer types. Because this analysis shows association rather than direction, both RFXAP-to-partner and partner-to-RFXAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFXAP versus HMGB1 in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RFXAP→partner) and Y-score (partner→RFXAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HMGB1 →	+0.313	+0.725	<.001	<.001	3	6
BRCA	GPALPP1 →	+0.371	+0.523	<.001	<.001	3	5
LSCC	ZMYM2 →	+0.451	+0.727	<.001	<.001	3	5
GBM	ARHGEF7 →	+0.216	+0.356	<.001	<.001	3	4
HNSC	RNASEH2A →	+0.381	+0.819	<.001	<.001	3	4
HNSC	RNASEH2B →	+0.523	+0.969	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,166 associations by consensus.

RFXAP vs HMGB1 — LSCC

Explore this scatter interactively →