RFXAP

Across TCGA patient cohorts, RFXAP protein abundance is significantly associated with the RNA expression of many other genes, with 6,704 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RFXAP-associated genes across cancer lineages are RFX5, RPARP-AS1, and DCAF6. Each is linked with RFXAP in more than 4 cancer types. Because this analysis shows association rather than direction, both RFXAP-to-partner and partner-to-RFXAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFXAP versus RFX5 in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFXAP→partner) and Y-score (partner→RFXAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RFX5 →	+0.601	+0.300	<.001	.001	3	5
LSCC	RPARP-AS1 →	+0.500	+0.245	<.001	.007	3	4
HNSC	DCAF6 →	+0.776	+0.371	.002	.002	3	4
UCEC	PI4KB →	+0.584	+0.332	<.001	.002	3	4
LSCC	FAM117A →	+0.434	+0.238	<.001	<.001	3	3
LSCC	TMC2 →	+0.248	+0.337	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,704 associations by consensus.

RFXAP vs RFX5 — BRCA

Explore this scatter interactively →