RFXAP

Across TCGA cell cohorts, RFXAP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,884 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RFXAP-associated GO terms across cancer lineages are Protein desumoylation, Positive regulation of cytoplasmic mRNA processing body assembly, and Ribosomal protein import into nucleus. Each is linked with RFXAP in more than 13 cancer types. Because this analysis shows association rather than direction, both RFXAP-to-partner and partner-to-RFXAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein desumoylation grouped by RFXAP-low versus RFXAP-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RFXAP→partner) and Y-score (partner→RFXAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein desumoylation →	+0.093	+1.123	<.001	<.001	3	14
SOFT_TISSUE	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.104	+0.764	<.001	<.001	3	14
PANCREAS	Ribosomal protein import into nucleus →	+0.107	+0.845	<.001	<.001	3	13
PANCREAS	Mitotic spindle assembly →	+0.083	+1.008	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of hematopoietic stem cell differentiation →	+0.140	+1.001	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cilium assembly →	+0.084	+1.087	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,884 associations by consensus.

Protein desumoylation by RFXAP expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →