RFXANK

Across TCGA patient cohorts, RFXANK protein abundance is significantly associated with the RNA expression of many other genes, with 7,326 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RFXANK-associated genes across cancer lineages are RFX5, CHRDL1, and TLR5. Each is linked with RFXANK in more than 4 cancer types. Because this analysis shows association rather than direction, both RFXANK-to-partner and partner-to-RFXANK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFXANK versus RFX5 in HNSC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFXANK→partner) and Y-score (partner→RFXANK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RFX5 →	+0.582	+0.216	<.001	<.001	3	5
COAD	CHRDL1 →	+3.373	+0.557	.004	.006	3	4
COAD	TLR5 →	+1.222	+0.559	.002	.002	3	4
COAD	HLA-DMA →	+1.816	+0.536	.005	.006	2	5
COAD	TRAF1 →	+0.989	+0.524	.008	.006	3	4
HNSC	L3MBTL4 →	+0.894	+0.195	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,326 associations by consensus.

RFXANK vs RFX5 — HNSC

Explore this scatter interactively →