RFXANK

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RFXANK mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible RFXANK-associated genes across cancer lineages are Astrocytes. Each is linked with RFXANK in more than 1 cancer types. Because this analysis shows association rather than direction, both RFXANK-to-partner and partner-to-RFXANK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Astrocytes grouped by RFXANK-low versus RFXANK-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFXANK→partner) and Y-score (partner→RFXANK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMAstrocytes →+0.036+2.825.048.02731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Astrocytes by RFXANK expression — SKCM

Box plot of Astrocytes in RFXANK-low vs RFXANK-high samples in SKCM.

Explore this box plot interactively →

Exploration