RFXANK

Across TCGA cell cohorts, RFXANK RNA expression is significantly associated with the RNA expression of many other genes, with 9,162 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RFXANK-associated genes across cancer lineages are FKBP8, NDUFA13, and COPE. Each is linked with RFXANK in more than 17 cancer types. Because this analysis shows association rather than direction, both RFXANK-to-partner and partner-to-RFXANK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFXANK versus FKBP8 in URINARY_TRACT, with a Pearson correlation of 0.72.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFXANK→partner) and Y-score (partner→RFXANK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	FKBP8 →	+1.180	+1.041	<.001	<.001	3	18
LIVER	NDUFA13 →	+1.098	+1.148	.002	<.001	2	17
STOMACH	COPE →	+0.962	+1.148	<.001	<.001	3	15
LIVER	TMEM161A →	+1.599	+1.082	<.001	.002	2	16
LUNG_NSCLC_LUSC	C19orf53 →	+1.167	+1.029	<.001	.006	1	16
STOMACH	DDX49 →	+1.215	+1.167	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,162 associations by consensus.

RFXANK vs FKBP8 — URINARY_TRACT

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