RFWD3

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RFWD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,519 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RFWD3-associated proteins across cancer lineages are EDC4, SMC2, and TOP2A. Each is linked with RFWD3 in more than 9 cancer types. Because this analysis shows association rather than direction, both RFWD3-to-partner and partner-to-RFWD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFWD3 versus EDC4 in BRCA, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RFWD3→partner) and Y-score (partner→RFWD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAEDC4 →+0.244+0.613<.001<.001310
OVSMC2 →+0.619+0.856<.001<.00139
LSCCTOP2A →+0.879+0.678<.001<.00139
LUADNCAPH →+0.734+0.399<.001<.00139
UCECRRM2 →+0.781+0.464<.001<.00139
COADCHAF1B →+0.767+0.733.001.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,519 associations by consensus.

RFWD3 vs EDC4 — BRCA

Per-sample scatter of RFWD3 vs EDC4 in BRCA (Pearson r = 0.47).

Explore this scatter interactively →

Exploration