RFTN1

Across TCGA pan-cancer cohorts, RFTN1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RFTN1 data layer compared with 23 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RFTN1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RFTN1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LUAD show a favorable association.

UCEC, PDAC, and LUAD are the cancer types where RFTN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.776	0.974	.011	16	view →
PDAC	OS	Median	All	0.604	0.351	.002	14	view →
LUAD	DFS	Tertile	All	0.812	0.517	.006	12	view →
GBM	DFS	Median	All	0.659	0.772	.014	8	view →
CCRCC	DFS	Tertile	II,III,IV	0.732	0.496	.032	6	view →
LSCC	DFS	Quartile	II,III,IV	0.506	1.000	.003	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RFTN1–UCEC (DFS)

Open the UCEC breakdown →