RFTN1

Across TCGA cell cohorts, RFTN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,588 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RFTN1-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Positive regulation of cell-substrate junction organization, and Collagen biosynthetic process. Each is linked with RFTN1 in more than 11 cancer types. Because this analysis shows association rather than direction, both RFTN1-to-partner and partner-to-RFTN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of focal adhesion assembly grouped by RFTN1-low versus RFTN1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RFTN1→partner) and Y-score (partner→RFTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of focal adhesion assembly →	+0.188	+3.164	<.001	<.001	3	12
BONE	Positive regulation of cell-substrate junction organization →	+0.163	+3.094	<.001	<.001	3	11
BONE	Collagen biosynthetic process →	+0.232	+2.722	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Hemostasis →	+0.115	+2.614	.001	.007	3	11
LIVER	Renal filtration →	+0.310	+3.697	<.001	<.001	3	11
SOFT_TISSUE	Regulation of growth rate →	+0.445	+2.046	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,588 associations by consensus.

Positive regulation of focal adhesion assembly by RFTN1 expression — BONE

Explore this box plot interactively →