RFPL4B

Across TCGA patient cohorts, RFPL4B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,964 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RFPL4B-associated GO terms across cancer lineages are Myeloid cell homeostasis, Negative regulation of transferase activity, and Regulation of macroautophagy. Each is linked with RFPL4B in more than 13 cancer types. Because this analysis shows association rather than direction, both RFPL4B-to-partner and partner-to-RFPL4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myeloid cell homeostasis grouped by RFPL4B-low versus RFPL4B-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RFPL4B→partner) and Y-score (partner→RFPL4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Myeloid cell homeostasis →	+0.087	+0.316	<.001	<.001	3	14
ESCA	Negative regulation of transferase activity →	+0.053	+0.109	<.001	<.001	2	14
STAD	Regulation of macroautophagy →	+0.051	+0.161	<.001	<.001	3	12
STAD	Viral gene expression →	+0.057	+0.161	<.001	<.001	3	12
STAD	Cytoplasmic pattern recognition receptor signaling pathway →	+0.076	+0.224	<.001	.001	3	12
STAD	TOR signaling →	+0.048	+0.163	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,964 associations by consensus.

Myeloid cell homeostasis by RFPL4B expression — STAD

Explore this box plot interactively →