RFPL4B

Across TCGA cell cohorts, RFPL4B RNA expression is significantly associated with the go_rna of many other GO terms, with 789 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible RFPL4B-associated GO terms across cancer lineages are Protein activation cascade, Skeletal myofibril assembly, and Amino acid import across plasma membrane. Each is linked with RFPL4B in more than 4 cancer types. Because this analysis shows association rather than direction, both RFPL4B-to-partner and partner-to-RFPL4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein activation cascade grouped by RFPL4B-low versus RFPL4B-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RFPL4B→partner) and Y-score (partner→RFPL4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Protein activation cascade →	+0.306	+0.103	<.001	.003	3	5
LUNG_NSCLC_LUSC	Skeletal myofibril assembly →	+0.296	+0.051	.001	.003	3	4
LUNG_NSCLC_LUSC	Amino acid import across plasma membrane →	-0.172	-0.046	<.001	.001	3	4
BREAST	Biological process involved in interaction with host →	+0.105	+0.262	<.001	.009	3	4
LUNG_NSCLC_LUSC	Negative regulation of cellular response to transforming growth factor beta stimulus →	+0.326	+0.053	.001	.009	3	4
STOMACH	Blood coagulation, extrinsic pathway →	+0.921	+0.070	.003	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 789 associations by consensus.

Protein activation cascade by RFPL4B expression — BREAST

Explore this box plot interactively →