RFPL4B

Across TCGA cell cohorts, RFPL4B mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible RFPL4B-associated genes across cancer lineages are OBP2B, NPSR1, and KRTAP12-3. Each is linked with RFPL4B in more than 1 cancer types. Because this analysis shows association rather than direction, both RFPL4B-to-partner and partner-to-RFPL4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OBP2B grouped by RFPL4B-low versus RFPL4B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFPL4B→partner) and Y-score (partner→RFPL4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OBP2B →	+0.057	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	NPSR1 →	+0.033	+4.152	<.001	.009	3	1
BLOOD_Leukemia	KRTAP12-3 →	+0.092	+4.539	<.001	.007	3	1
SKIN	GOLGA8F →	+0.019	+3.217	<.001	.006	3	1
SKIN	SMIM43 →	+0.531	+3.426	<.001	.007	3	1
SKIN	OPRPN →	+0.037	+4.047	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

OBP2B by RFPL4B expression — BLOOD_Leukemia

Explore this box plot interactively →