RFPL4B

Across TCGA cell cohorts, RFPL4B mutation is significantly associated with the mutation status of many other genes, with 349 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RFPL4B-associated genes across cancer lineages are HAUS5, ZNF365, and DHX37. Each is linked with RFPL4B in more than 2 cancer types. Because this analysis shows association rather than direction, both RFPL4B-to-partner and partner-to-RFPL4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HAUS5 grouped by RFPL4B-low versus RFPL4B-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFPL4B→partner) and Y-score (partner→RFPL4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	HAUS5 →	+4.429	+5.247	.005	.005	1	3
SKIN	ZNF365 →	+3.532	+3.357	.005	.005	1	2
SKIN	DHX37 →	+3.532	+3.357	.005	.005	1	2
SKIN	RAPGEF6 →	+3.117	+3.117	.009	.009	1	2
SKIN	LGI3 →	+4.117	+3.638	.002	.002	1	2
SKIN	FSTL5 →	+3.210	+3.548	.001	.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 349 associations by consensus.

HAUS5 by RFPL4B expression — BLOOD_Lymphoma

Explore this box plot interactively →