RFPL4AP3

Across TCGA pan-cancer cohorts, RFPL4AP3 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RFPL4AP3 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher RFPL4AP3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RFPL4AP3 expression acts as an unfavorable survival marker.

LIHC, KIRC, and THYM are the cancer types where RFPL4AP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	All	0.144	0.569	<.001	63	view →
KIRC	DFS	Tertile	All	0.522	0.645	.009	39	view →
THYM	DFS	Tertile	II,III,IV	0.145	0.873	<.001	18	view →
KIRP	DFS	Tertile	All	0.411	0.794	.005	18	view →
HNSC	DFS	Tertile	II,III,IV	0.431	0.675	.033	18	view →
BLCA	DFS	Tertile	III,IV	0.196	0.574	.025	9	view →
STAD	DFS	Tertile	IV	0.144	0.444	.012	9	view →
ESCA	DFS	Tertile	All	0.346	0.528	.020	9	view →
COAD	DFS	Tertile	II,III,IV	0.302	0.651	.042	9	view →
SARC	DFS	Tertile	All	0.186	0.519	.028	9	view →
LGG	DFS	Tertile	All	0.533	0.762	.028	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

RFPL4AP3–LIHC (OS)

Open the LIHC breakdown →