Q-omics provides the consensus-scored RFPL4AP3 profile across patient tissues and cancer cell-line models. RFPL4AP3 expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in LIHC. Additionally, RFPL4AP3 RNA expression shows 6,148 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight LIHC, and STAD as cancer lineages where RFPL4AP3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RFPL4AP3 survival associations across molecular data types. RFPL4AP3 RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RFPL4AP3 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	11	LIHC (63)	view →

This table ranks reproducible RFPL4AP3 RNA expression–survival associations across cancer types. High RFPL4AP3 expression shows unfavorable associations in LIHC, KIRC, HNSC, THYM, KIRP and ESCA. The LIHC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LIHC as the clearest survival context for RFPL4AP3 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	All	0.144	0.569	<.001	63	view →
KIRC	DFS	Tertile	All	0.522	0.645	.009	39	view →
HNSC	DFS	Tertile	II,III,IV	0.431	0.675	.033	18	view →
THYM	DFS	Tertile	II,III,IV	0.145	0.873	<.001	18	view →
KIRP	DFS	Tertile	All	0.411	0.794	.005	18	view →
ESCA	DFS	Tertile	All	0.346	0.528	.020	9	view →

Pink = unfavorable, green = favorable. all 11 lineages →

RFPL4AP3-LIHC (OS)

Kaplan–Meier survival curve for RFPL4AP3 RNA expression in LIHC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RFPL4AP3 in patient tissues and cancer cell lines. In patient samples, RFPL4AP3 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	6,148	STAD (5888)	view →
Protein (mass-spec)	4,220	GBM (1973)	view →