RFPL4AL1

Across TCGA pan-cancer cohorts, RFPL4AL1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RFPL4AL1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RFPL4AL1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RFPL4AL1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and DLBC show a favorable association.

KICH, LUAD, and CESC are the cancer types where RFPL4AL1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	All	0.082	0.877	<.001	60	view →
LUAD	DFS	Tertile	III,IV	0.341	0.663	.008	36	view →
CESC	OS	Tertile	IV	0.093	0.620	<.001	36	view →
ACC	OS	Tertile	All	0.696	0.884	.005	36	view →
COAD	DFS	Tertile	III,IV	0.114	0.439	.004	30	view →
THYM	DFS	Tertile	All	0.704	0.949	.003	18	view →
READ	DFS	Tertile	IV	0.027	0.636	<.001	18	view →
PCPG	OS	Tertile	All	0.670	0.958	<.001	15	view →
ESCA	OS	Tertile	III,IV	0.589	0.358	.038	12	view →
LIHC	OS	Tertile	III,IV	0.424	0.678	.008	10	view →
LGG	OS	Tertile	All	0.545	0.803	.024	9	view →
THCA	OS	Tertile	All	0.576	0.959	.011	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RFPL4AL1–KICH (OS)

Open the KICH breakdown →