Across TCGA patient cohorts, RFPL3S mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RFPL3S-associated genes across cancer lineages are RNU6-1252P, ACTR3BP7, and YWHAQP9. Each is linked with RFPL3S in more than 1 cancer types. Because this analysis shows association rather than direction, both RFPL3S-to-partner and partner-to-RFPL3S results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFPL3S→partner) and Y-score (partner→RFPL3S) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-1252P →	+0.526	+7.741	<.001	.009	3	1
COAD	ACTR3BP7 →	+0.044	+7.741	<.001	.009	3	1
COAD	YWHAQP9 →	+0.107	+7.741	.005	.009	3	1
COAD	TSPY15P →	+0.084	+7.741	<.001	.009	3	1
COAD	RNA5SP489 →	+0.518	+7.741	<.001	.009	3	1
COAD	OR5J7P →	+0.314	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

RFPL3S survival (RNA) · tumor vs normal (RNA) · all RFPL3S data types