RFPL2

Across TCGA patient cohorts, RFPL2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,527 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible RFPL2-associated genes across cancer lineages are SPOCK1, HOXA1, and GRB10. Each is linked with RFPL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RFPL2-to-partner and partner-to-RFPL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFPL2 versus SPOCK1 in CCRCC, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFPL2→partner) and Y-score (partner→RFPL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SPOCK1 →	+3.912	+0.998	<.001	.001	3	3
CCRCC	HOXA1 →	+1.053	+0.788	.002	.003	3	2
GBM	GRB10 →	+1.174	+0.314	<.001	.006	3	2
CCRCC	PAPSS2 →	+1.488	+1.026	.001	.001	3	2
CCRCC	KDELR3 →	+2.195	+0.906	.001	.003	3	2
CCRCC	RGCC →	-1.947	-0.961	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,527 associations by consensus.

RFPL2 vs SPOCK1 — CCRCC

Explore this scatter interactively →