Across TCGA pan-cancer cohorts, RFPL1S RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RFPL1S data layer.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RFPL1S RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RFPL1S expression acts as an unfavorable survival marker, although some lineages such as CHOL and HNSC show a favorable association.
UCEC, CHOL, and LIHC are the cancer types where RFPL1S RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.