RFPL1

Across TCGA patient cohorts, RFPL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,992 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RFPL1-associated GO terms across cancer lineages are Microtubule depolymerization, Mitochondrial RNA metabolic process, and Macromolecule methylation. Each is linked with RFPL1 in more than 10 cancer types. Because this analysis shows association rather than direction, both RFPL1-to-partner and partner-to-RFPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule depolymerization grouped by RFPL1-low versus RFPL1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RFPL1→partner) and Y-score (partner→RFPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Microtubule depolymerization →	+0.060	+0.117	<.001	<.001	3	11
STAD	Mitochondrial RNA metabolic process →	+0.082	+0.063	<.001	<.001	3	11
STAD	Macromolecule methylation →	+0.064	+0.043	<.001	.002	3	11
STAD	Regulation of microtubule cytoskeleton organization →	+0.070	+0.060	<.001	<.001	3	11
STAD	Transport along microtubule →	+0.064	+0.061	<.001	<.001	3	11
STAD	Peptidyl-lysine modification →	+0.064	+0.045	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,992 associations by consensus.

Microtubule depolymerization by RFPL1 expression — ESCA

Explore this box plot interactively →