RFPL1

Across TCGA cell cohorts, RFPL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,105 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RFPL1-associated GO terms across cancer lineages are Proteasomal ubiquitin-independent protein catabolic process, ATP metabolic process, and Neurofilament bundle assembly. Each is linked with RFPL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both RFPL1-to-partner and partner-to-RFPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proteasomal ubiquitin-independent protein catabolic process grouped by RFPL1-low versus RFPL1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RFPL1→partner) and Y-score (partner→RFPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Proteasomal ubiquitin-independent protein catabolic process →	+0.082	+0.072	<.001	.002	3	8
BONE	ATP metabolic process →	+0.079	+0.199	<.001	.005	3	7
BONE	Neurofilament bundle assembly →	+1.216	+0.225	<.001	.002	3	6
LUNG_NSCLC_LUAD	Postsynaptic intermediate filament cytoskeleton organization →	+0.960	+0.119	<.001	.005	3	6
SOFT_TISSUE	Regulation of cholesterol efflux →	+0.089	+0.139	<.001	.009	3	6
BONE	Purine ribonucleoside triphosphate metabolic process →	+0.076	+0.199	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,105 associations by consensus.

Proteasomal ubiquitin-independent protein catabolic process by RFPL1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →