RFLNA

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RFLNA RNA expression is significantly associated with the protein abundance of many other proteins, with 11,956 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible RFLNA-associated proteins across cancer lineages are PLOD1, RCN3, and SULF1. Each is linked with RFLNA in more than 5 cancer types. Because this analysis shows association rather than direction, both RFLNA-to-partner and partner-to-RFLNA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFLNA versus PLOD1 in OV, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RFLNA→partner) and Y-score (partner→RFLNA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVPLOD1 →+0.726+1.722<.001<.00136
OVRCN3 →+0.678+1.410<.001<.00136
OVSULF1 →+0.863+1.411<.001<.00136
OVTHBS2 →+1.226+1.243<.001<.00136
CCRCCACTN1 →+0.530+0.663<.001.00236
OVC1R →+0.662+1.220<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,956 associations by consensus.

RFLNA vs PLOD1 — OV

Per-sample scatter of RFLNA vs PLOD1 in OV (Pearson r = 0.48).

Explore this scatter interactively →

Exploration