RFLNA

Across TCGA patient cohorts, RFLNA protein abundance is significantly associated with the RNA expression of many other genes, with 5,769 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RFLNA-associated genes across cancer lineages are SYDE1, COL1A1, and MYL9. Each is linked with RFLNA in more than 3 cancer types. Because this analysis shows association rather than direction, both RFLNA-to-partner and partner-to-RFLNA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFLNA versus SYDE1 in BRCA, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFLNA→partner) and Y-score (partner→RFLNA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SYDE1 →	+0.632	+0.411	<.001	<.001	3	4
BRCA	COL1A1 →	+1.664	+0.451	<.001	<.001	3	4
BRCA	MYL9 →	+1.311	+0.539	<.001	<.001	3	3
BRCA	MXRA5 →	+1.195	+0.427	<.001	.003	3	3
LSCC	WNT2 →	+0.809	+0.461	<.001	<.001	3	3
BRCA	PCOLCE →	+1.186	+0.472	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,769 associations by consensus.

RFLNA vs SYDE1 — BRCA

Explore this scatter interactively →