RFLNA

Across TCGA cell cohorts, RFLNA mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible RFLNA-associated genes across cancer lineages are SPATA31A1 and PIRT. Each is linked with RFLNA in more than 1 cancer types. Because this analysis shows association rather than direction, both RFLNA-to-partner and partner-to-RFLNA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA31A1 grouped by RFLNA-low versus RFLNA-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFLNA→partner) and Y-score (partner→RFLNA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SPATA31A1 →	+0.030	+4.129	<.001	.007	3	1
STOMACH	PIRT →	+0.084	+4.169	<.001	.005	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SPATA31A1 by RFLNA expression — STOMACH

Explore this box plot interactively →