RFK

Across TCGA patient cohorts, RFK protein abundance is significantly associated with the RNA expression of many other genes, with 8,616 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible RFK-associated genes across cancer lineages are CARNMT1, RPSAP9, and ABHD17B. Each is linked with RFK in more than 4 cancer types. Because this analysis shows association rather than direction, both RFK-to-partner and partner-to-RFK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFK versus CARNMT1 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFK→partner) and Y-score (partner→RFK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CARNMT1 →	+0.563	+0.369	.005	.004	3	5
UCEC	RPSAP9 →	+0.590	+0.485	.003	<.001	3	5
BRCA	ABHD17B →	+0.493	+0.306	.004	.007	3	5
UCEC	FERMT1 →	+0.988	+0.277	<.001	.002	3	4
UCEC	PLEKHA1 →	+0.745	+0.432	<.001	<.001	3	4
UCEC	KLHDC7A →	+1.117	+0.480	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,616 associations by consensus.

RFK vs CARNMT1 — BRCA

Explore this scatter interactively →