RFESD

Across TCGA patient cohorts, RFESD protein abundance is significantly associated with the RNA expression of many other genes, with 1,927 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RFESD-associated genes across cancer lineages are HBA1, HBA2, and HBB. Each is linked with RFESD in more than 5 cancer types. Because this analysis shows association rather than direction, both RFESD-to-partner and partner-to-RFESD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFESD versus HBA1 in GBM, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFESD→partner) and Y-score (partner→RFESD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HBA1 →	+1.530	+0.501	<.001	<.001	3	6
GBM	HBA2 →	+1.617	+0.557	<.001	<.001	3	5
GBM	HBB →	+1.634	+0.524	<.001	<.001	3	5
CCRCC	HEMGN →	+0.515	+0.477	<.001	<.001	3	4
CCRCC	SLC4A1 →	+0.676	+0.517	<.001	<.001	3	4
BRCA	CTSG →	+1.045	+0.518	.006	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,927 associations by consensus.

RFESD vs HBA1 — GBM

Explore this scatter interactively →