RFC5

Across TCGA patient cohorts, RFC5 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,396 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RFC5-associated proteins across cancer lineages are CDK1, SMC4, and MAD2L1. Each is linked with RFC5 in more than 9 cancer types. Because this analysis shows association rather than direction, both RFC5-to-partner and partner-to-RFC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFC5 versus CDK1 in OV, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RFC5→partner) and Y-score (partner→RFC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CDK1 →	+0.802	+0.611	<.001	<.001	3	10
LSCC	SMC4 →	+0.654	+0.920	<.001	<.001	3	10
UCEC	MAD2L1 →	+0.566	+0.524	<.001	<.001	3	10
OV	MCM2 →	+0.820	+0.793	<.001	<.001	3	10
OV	MCM3 →	+0.945	+0.735	<.001	<.001	3	10
LUAD	MCM4 →	+0.808	+0.672	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,396 associations by consensus.

RFC5 vs CDK1 — OV

Explore this scatter interactively →