RFC5

Across TCGA patient cohorts, RFC5 protein abundance is significantly associated with the protein abundance of many other proteins, with 36,356 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RFC5-associated proteins across cancer lineages are RFC2, RFC3, and RFC4. Each is linked with RFC5 in more than 9 cancer types. Because this analysis shows association rather than direction, both RFC5-to-partner and partner-to-RFC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFC5 versus RFC2 in LSCC, with a Pearson correlation of 0.96.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RFC5→partner) and Y-score (partner→RFC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC2 →	+0.639	+0.591	<.001	<.001	3	10
HNSC	RFC3 →	+0.446	+0.579	<.001	<.001	3	10
LSCC	RFC4 →	+0.751	+0.602	<.001	<.001	3	10
LUAD	MCM2 →	+0.935	+0.428	<.001	<.001	3	10
LUAD	MCM4_S120 →	+1.176	+0.252	<.001	<.001	3	10
GBM	RBM15 →	+0.288	+0.442	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 36,356 associations by consensus.

RFC5 vs RFC2 — LSCC

Explore this scatter interactively →