RFC4

Across TCGA cell cohorts, RFC4 protein abundance is significantly associated with the RNA expression of many other genes, with 6,221 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RFC4-associated genes across cancer lineages are TRAPPC6B, ACVR2B, and MAGI1. Each is linked with RFC4 in more than 2 cancer types. Because this analysis shows association rather than direction, both RFC4-to-partner and partner-to-RFC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFC4 versus TRAPPC6B in PANCREAS, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFC4→partner) and Y-score (partner→RFC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	TRAPPC6B →	+1.069	+1.572	.006	.004	3	3
LUNG_NSCLC_LUAD	ACVR2B →	+0.887	+2.357	.001	.005	3	2
LUNG_NSCLC_LUAD	MAGI1 →	+1.053	+1.863	<.001	.002	3	2
LUNG_NSCLC_LUAD	CYP51A1 →	+1.309	+1.732	.001	.009	3	2
LUNG_NSCLC_LUAD	CDS1 →	+0.705	+1.920	.002	.005	3	2
LUNG_NSCLC_LUAD	ASAH2 →	+0.934	+1.863	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,221 associations by consensus.

RFC4 vs TRAPPC6B — PANCREAS

Explore this scatter interactively →