REX1BD

Across TCGA patient cohorts, REX1BD RNA expression is significantly associated with the go_rna of many other GO terms, with 7,157 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible REX1BD-associated GO terms across cancer lineages are [4Fe-4S] cluster assembly, Ribosome-associated ubiquitin-dependent protein catabolic process, and Establishment of mitotic sister chromatid cohesion. Each is linked with REX1BD in more than 25 cancer types. Because this analysis shows association rather than direction, both REX1BD-to-partner and partner-to-REX1BD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, [4Fe-4S] cluster assembly grouped by REX1BD-low versus REX1BD-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (REX1BD→partner) and Y-score (partner→REX1BD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	[4Fe-4S] cluster assembly →	+0.101	+0.964	<.001	<.001	3	26
DLBC	Ribosome-associated ubiquitin-dependent protein catabolic process →	-0.107	-0.963	<.001	<.001	3	25
DLBC	Establishment of mitotic sister chromatid cohesion →	-0.095	-0.805	<.001	<.001	3	25
ACC	Regulation of lysosome size →	+0.028	+0.767	<.001	<.001	3	24
DLBC	Iron-sulfur cluster assembly →	+0.061	+0.889	<.001	<.001	1	26
READ	tRNA thio-modification →	+0.094	+1.307	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,157 associations by consensus.

[4Fe-4S] cluster assembly by REX1BD expression — DLBC

Explore this box plot interactively →