REX1BD

Across TCGA pan-cancer cohorts, REX1BD RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated REX1BD data layer compared with 3 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher REX1BD RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated REX1BD expression acts as an unfavorable survival marker, although some lineages such as HNSC and PAAD show a favorable association.

ACC, UVM, and KIRC are the cancer types where REX1BD RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.249	0.652	<.001	124	view →
UVM	DFS	Quartile	II,III,IV	0.310	0.763	<.001	93	view →
KIRC	DFS	Median	All	0.749	0.866	<.001	82	view →
HNSC	OS	Tertile	II,III,IV	0.851	0.690	<.001	47	view →
LGG	DFS	Median	All	0.654	0.807	<.001	40	view →
PAAD	OS	Quartile	All	0.619	0.241	.004	21	view →
PRAD	DFS	Median	All	0.710	0.863	<.001	18	view →
CHOL	OS	Median	III,IV	1.000	0.286	.008	15	view →
DLBC	DFS	Median	III,IV	0.140	0.917	.010	14	view →
COAD	DFS	Tertile	II,III,IV	0.875	0.697	.005	13	view →
KICH	DFS	Tertile	III,IV	0.056	0.819	.010	13	view →
BLCA	DFS	Median	All	0.557	0.458	.027	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

REX1BD–ACC (DFS)

Open the ACC breakdown →