REX1BD

Across TCGA patient cohorts, REX1BD mutation is significantly associated with the RNA expression of many other genes, with 63 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible REX1BD-associated genes across cancer lineages are MIR4287, RNA5SP223, and RNA5SP519. Each is linked with REX1BD in more than 1 cancer types. Because this analysis shows association rather than direction, both REX1BD-to-partner and partner-to-REX1BD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4287 grouped by REX1BD-low versus REX1BD-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REX1BD→partner) and Y-score (partner→REX1BD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4287 →	+0.340	+4.660	<.001	.003	3	2
UCEC	RNA5SP223 →	+0.313	+3.997	<.001	.009	3	2
UCEC	RNA5SP519 →	+0.903	+3.246	<.001	.008	3	2
UCEC	LINC01338 →	+0.733	+2.993	<.001	.006	3	1
UCEC	MIR3621 →	+0.676	+4.133	<.001	<.001	3	1
UCEC	MIR5688 →	+0.346	+3.621	.006	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

MIR4287 by REX1BD expression — UCEC

Explore this box plot interactively →