REX1BD

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, REX1BD mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible REX1BD-associated genes across cancer lineages are B-cells and CD4+ memory T-cells. Each is linked with REX1BD in more than 1 cancer types. Because this analysis shows association rather than direction, both REX1BD-to-partner and partner-to-REX1BD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B-cells grouped by REX1BD-low versus REX1BD-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REX1BD→partner) and Y-score (partner→REX1BD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECB-cells →+0.073+2.310<.001.02631
UCECCD4+ memory T-cells →+0.028+2.354.011.02431
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

B-cells by REX1BD expression — UCEC

Box plot of B-cells in REX1BD-low vs REX1BD-high samples in UCEC.

Explore this box plot interactively →

Exploration