REX1BD

Across TCGA cell cohorts, REX1BD RNA expression is significantly associated with the go_rna of many other GO terms, with 3,467 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible REX1BD-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Regulation of sphingolipid biosynthetic process, and Energy coupled proton transmembrane transport, against electrochemical gradient. Each is linked with REX1BD in more than 12 cancer types. Because this analysis shows association rather than direction, both REX1BD-to-partner and partner-to-REX1BD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by REX1BD-low versus REX1BD-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (REX1BD→partner) and Y-score (partner→REX1BD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.081	+1.347	<.001	<.001	3	13
SKIN	Regulation of sphingolipid biosynthetic process →	+0.095	+1.846	<.001	<.001	3	12
OESOPHAGUS	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.098	+0.924	.001	.006	3	12
OESOPHAGUS	Electron transport coupled proton transport →	+0.098	+0.924	.001	.006	3	12
SKIN	Cellular response to methylglyoxal →	+0.165	+1.903	<.001	<.001	3	11
SKIN	Cellular detoxification of methylglyoxal →	+0.165	+1.903	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,467 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by REX1BD expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →