REX1BD

Across TCGA cell cohorts, REX1BD mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible REX1BD-associated genes across cancer lineages are ADAM30, DMRTC2, and OR9K2. Each is linked with REX1BD in more than 1 cancer types. Because this analysis shows association rather than direction, both REX1BD-to-partner and partner-to-REX1BD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADAM30 grouped by REX1BD-low versus REX1BD-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REX1BD→partner) and Y-score (partner→REX1BD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ADAM30 →	+0.017	+5.569	<.001	.001	3	1
BLOOD_Leukemia	DMRTC2 →	+0.023	+4.539	.001	.007	3	1
BLOOD_Leukemia	OR9K2 →	+0.016	+4.539	<.001	.007	3	1
BLOOD_Leukemia	OR1N2 →	+0.034	+4.705	<.001	.003	3	1
BLOOD_Leukemia	OR52E4 →	+0.019	+5.786	<.001	<.001	3	1
BLOOD_Leukemia	OR56A4 →	+0.006	+4.874	.009	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

ADAM30 by REX1BD expression — BLOOD_Leukemia

Explore this box plot interactively →