REV1

Across TCGA patient cohorts, REV1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,591 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible REV1-associated proteins across cancer lineages are HNRNPLL, WDR5, and CEBPB. Each is linked with REV1 in more than 6 cancer types. Because this analysis shows association rather than direction, both REV1-to-partner and partner-to-REV1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, REV1 versus HNRNPLL in GBM, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (REV1→partner) and Y-score (partner→REV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HNRNPLL →	+0.299	+0.273	<.001	<.001	3	7
GBM	WDR5 →	+0.310	+0.271	<.001	<.001	3	6
CCRCC	CEBPB →	-0.656	-0.399	<.001	<.001	3	6
GBM	FMNL1 →	-0.565	-0.266	<.001	<.001	3	6
GBM	FUBP3 →	+0.191	+0.234	.002	.005	3	6
GBM	MAN2A1 →	-0.459	-0.232	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,591 associations by consensus.

REV1 vs HNRNPLL — GBM

Explore this scatter interactively →