RETSAT

Across TCGA cell cohorts, RETSAT RNA expression is significantly associated with the go_rna of many other GO terms, with 4,849 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RETSAT-associated GO terms across cancer lineages are Lipid catabolic process, Glycerophospholipid metabolic process, and Response to insulin. Each is linked with RETSAT in more than 11 cancer types. Because this analysis shows association rather than direction, both RETSAT-to-partner and partner-to-RETSAT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipid catabolic process grouped by RETSAT-low versus RETSAT-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RETSAT→partner) and Y-score (partner→RETSAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Lipid catabolic process →	+0.045	+0.951	<.001	<.001	3	12
SKIN	Glycerophospholipid metabolic process →	+0.038	+0.912	.001	<.001	3	11
BONE	Response to insulin →	+0.052	+1.073	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Glycerophospholipid biosynthetic process →	+0.046	+0.927	<.001	<.001	3	10
SOFT_TISSUE	Vacuolar transport →	+0.058	+0.820	<.001	.001	3	10
LUNG_NSCLC_LUAD	Lipid oxidation →	+0.069	+0.819	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,849 associations by consensus.

Lipid catabolic process by RETSAT expression — SKIN

Explore this box plot interactively →